| Name | Organization Type | Region | Description |
|---|---|---|---|
| ABEC, Inc. | Company | Northeast | Manufacturer of cGMP bioreactors and fermentors |
| Adhesives Research, Inc. | Company | Southcentral | Manufacturer of pressure sensitive adhesive tapes and specialty coatings, films and laminate products |
| Adhezion Biomedical, LLC | Company | Southeast | Development & commercialization of proprietary, highly differentiated cyanoacrylate products |
| Advanced Research Systems, Inc. | Company | Northeast | Designs and develops cryogenic equipment and supplies |
| Advanced Scientifics,Inc. | Company | Northcentral | Manufacturer of Medical Devices |
| Aesculap U.S. Headquarters | Company | Northeast | Division of B. Braun |
| Ahlstrom Filtration LLC | Company | Southcentral | Manufacturer of specialty filter papers |
| Air Products and Chemicals, Inc. | Company | Northeast | Producer of specialty gases, chemicals and equipment |
| Albright College | Higher Education | Northeast | |
| Allegheny Bradford Corp | Company | Northwest | Custom stainless steel products for pharmaceutical and other ultra pure applications. |
| Allegheny College | Higher Education | Northwest | |
| Alson Research, Ltd | Company | Northeast | Ophthalmic device manufacturer |
| Altoona-Blair County Development Corporation | Support Services | Northcentral | Economic development agency |
| Alvernia College | Higher Education | Northeast | |
| American Analytical | Company | Northcentral | Custom products/manufacturing for the pharmaceutical industry |
| Analytical Laboratory Services, Inc. | Company | Southcentral | Environmental Testing Lab |
| Angiotech Pharmaceuticals, Inc. | Company | Northeast | Manufacturer of surgical/medical instruments |
| APD Life Sciences | Company | Northcentral | Developer of nanoparticles for biological studies |
| Apeliotus Vision Science | Company | Southcentral | Non-invasive diagnostic test for age-related macular degeneration |
| Apogee Biotechnology Corporation | Company | Southcentral | Drug development (HIV, cancer) |
| Applied Research & Photonics, Inc. (ARP) | Company | Southcentral | Developing a nanophotonic integratedcircuit (nPIC©), a chip based platform technology |
| Applied Separations, Inc. | Company | Northeast | Sample preparation and equipment |
| Aptagen, LLC | Company | Southcentral | |
| Arista Biologicals, Inc. | Company | Northeast | Manufacturer of diagnostic reagents and equipment |
| Arrow International, Inc. | Company | Northeast | Manufacturer of catheters and other medical devices |
| Azevan Pharmaceuticals, Inc. | Company | Northeast | Drug discovery and development for CNS disorders |
| B.Braun Medical, Inc. | Company | Northeast | Manufacturer of medical and surgical supplies |
| Ben Franklin Technology Partners-Central | Support Services | Northcentral | Support for technology-based entrepreneurs |
| Ben Franklin Technology Partners-NEP | Support Services | Northeast | Support for technology-based entrepreneurs |
| Better Bowls LLC | Company | Southcentral | Developer of great tasting food to prevent or manage health issues |
| Bio Med Sciences, Inc. | Company | Northeast | Developer of wound care and scar management materials |
| BioSpectra, Inc. | Company | Northeast | Producer of cGMP compliant biological buffers |
| Bloomsburg University | Higher Education | Northcentral | |
| Bucknell University | Higher Education | Northcentral | |
| C & L Instruments, Inc. | Company | Southcentral | Manufacturer of fluorescence devices |
| Calcigen Corporation | Company | Northeast | Developer of novel hyaluronic acid production methods |
| Calvert Laboratories, Inc. | Company | Northcentral | Provides assistance in bringing new discovery compounds to the Investigational New Drug phase of the drug development cycle |
| Cedar Crest College | Higher Education | Northeast | |
| Central Pennsylvania College | Higher Education | Southcentral | |
| Chamber of Business and Industry of Centre Co. | Support Services | Northcentral | Economic development agency |
| Chemical Solutions, Ltd | Company | Southcentral | Laboratory specializing in ultra trace level elemental analysis |
| Clarion University | Higher Education | Northwest | |
| Clarkson Chromatography Products Inc. | Company | Northcentral | Liquid chromatography media |
| Cocalico Biologicals, Inc. | Company | Southeast | Custom antibody production |
| Commonwealth Medical College | Higher Education | Northeast | |
| Conductive Technologies, Inc. | Company | Southcentral | Manufacturer of circuitry-based biosensors |
| Copperhead Chemical Company, Inc. | Company | Northeast | Manufacturer of nitroglycerin for pharmaceutical products |
| Coulbourn Instruments | Company | Northeast | Instrumentation for pharmaceutical Industry, CROs and academia |
| Covance, Inc. | Company | Southeast | Provider of drug development services |
| Covance Research Products (CRP), Inc. | Company | Southeast | Purpose-bred research animals and related services. |
| Deltagen BioServices, Inc. | Company | Southeast | Laboratories - Research and Development |
| Dentsply International, Inc. | Company | Southcentral | Manufacturer of dental equipment |
| Dentsply Trubyte | Company | Southcentral | Manufacturer of removable dentures |
| Department of Community & Economic Development | Support Services | Statewide | Statewide economic development agency |
| DeSales University | Higher Education | Northeast | |
| DIApedia | Company | Northcentral | Developer of footwear and other devices for diabetics |
| Dickinson College | Higher Education | Southcentral | |
| Digestive Care, Inc. | Company | Northeast | Manufacturer of Pancreacarb |
| DME Alliance, Inc. | Company | Northeast | Turnkey engineering services for process facilities in the life sciences sector |
| Drucker Co./QBC Diagnostics | Company | Northcentral | Manufacturer of centrifuges |
| Dyets, Inc. | Company | Northeast | Experimental diets and ingredients for lab animals |
| Eastern University | Higher Education | Southcentral | |
| East Stroudsburg University | Higher Education | Northeast | |
| Edinboro University | Higher Education | Northwest | |
| Elizabethtown College | Higher Education | Southcentral | |
| Entopath, Inc. | Company | Northeast | Insect-derived recombinant proteins |
| Fisher Clinical Services | Company | Northeast | Clinical trials support, including packaging, labeling, storage and distribution |
| Franklin and Marshall College | Higher Education | Southcentral | |
| Gallery Science, LLC | Company | Northcentral | Supplier of medical equipment and devices |
| Gannon University | Higher Education | Northwest | |
| Geisinger Health System | Higher Education | Northcentral | |
| Gettig Pharmaceutical Instrument Company | Company | Northcentral | Manufacturer of pharmaceutical Instrumentation |
| Gettysburg College | Higher Education | Southcentral | |
| GrantAdler Corporation | Company | Northeast | Manufacturer of High-Integrity Catheter System |
| Grove City College | Higher Education | Northwest | |
| Harrisburg Regional Chamber & CREDC | Support Services | Southcentral | Economic development agency |
| Harrisburg University of Science and Technology | Higher Education | Southcentral | |
| Illuminex Corporation | Company | Southcentral | Developer of nanowire optical biomarker detector |
| IMC (Inernational Medical Consultants) | Company | Northeast | International medical consultants |
| Immuna Care Corp. | Company | Northeast | Detection and prevention of estrogen-related diseases |
| Immunomic Therapeutics, Inc. | Company | Southcentral | Vaccine development company |
| Indigo Biosciences LLC | Company | Northcentral | Contract research organization |
| Industrial Science & Technology Network, Inc. | Company | Southcentral | Development of organic/inorganic nanocomposites for biotechnology |
| Innovation Partnership | Support Services | Statewide | SBIR Assistance |
| INRange Systems, Inc. | Company | Northcentral | Remote medication management systems |
| Integra Life Sciences | Company | Southcentral | Medical devices and technologies |
| Integrated BioSciences, inc. | Company | Southcentral | Contract manufacturer of medical devices |
| International Medical Consultants | Company | Northeast | Pharmaceutical/biotechnology drug development organization |
| Invatec, Inc. | Company | Northeast | Marketing and distribution of medical devices |
| ISS Pharmaceuticals | Company | Northeast | Early stage drug discovery research company |
| Juniata College | Higher Education | Northcentral | |
| Keystone Nano, Inc. | Company | Northcentral | Creates 2nm to 20nm particles containing new drugs |
| Kutztown Small Business Development Center | Support Services | Southcentral | Assistance for small businesses |
| Kutztown University | Higher Education | Northcentral | |
| Lafayette College | Higher Education | Northeast | |
| Lake Erie College of Osteopathic Medicine | Higher Education | Northwest | |
| Lampire Biological Laboratories, Inc. | Company | Northcentral | Supplier of antibodies, reagents and animal blood products |
| Lancaster General College of Nursing & Health Sciences | Higher Education | Southcentral | |
| Lancaster Laboratories | Company | Southcentral | Analytical services for pharmaceutical industry |
| LCM Technologies, Inc. | Company | Northcentral | DNA sequencing using free-solution electrophoresis |
| Lebanon Valley College | Higher Education | Southcentral | |
| Lehigh University | Higher Education | Northeast | |
| Lehigh University Small Business Development Center | Support Services | Northeast | Assistance for small businesses |
| Lehigh Valley Technologies, Inc. | Company | Northeast | Production of generic and OTC drugs |
| Lock Haven University | Higher Education | Northcentral | |
| Lonza, Inc. | Company | Northcentral | Production of chemicals for life sciences and other industries |
| Lycoming College | Higher Education | Northcentral | |
| Maintenance Reliability Group, LLC | Company | Southcentral | Performs lubricant analysis for biomedical research facilities |
| Marywood University | Higher Education | Northeast | |
| Matreya, LLC | Company | Northcentral | Manufacturer of lipids for biochemical research |
| Mercyhurst College | Higher Education | Northwest | |
| Messiah College | Higher Education | Southcentral | |
| Micromechatronics Inc. | Company | Northcentral | Producer of actuators and transducers |
| Millersville University | Higher Education | Southcentral | |
| Miltex | Company | Southcentral | |
| Mitotyping Technologies, LLC | Company | Northcentral | Forensic mitochondrial DNA analysis |
| Moravian College | Higher Education | Northeast | |
| MPI Research | Company | Northcentral | Contract R&D and research support Services |
| Muhlenberg College | Higher Education | Northeast | |
| Murata Business Center | Support Services | Southcentral | Business incubator |
| NanoHorizons, Inc. | Company | Northcentral | Developer and manufacturer of nanotechnology particles and products |
| National Venture Capital Association | Support Services | National | Venture capital industry association |
| Noble Biomaterials, Inc. | Company | Northeast | Manufacturer of biomaterials |
| Northampton Community College | Higher Education | Northeast | |
| OraSure Technologies, Inc. | Company | Northeast | Medical diagnostics |
| Pacer Pumps | Company | Southcentral | Division of ASM Industries: manufacturer of industrial pumps |
| Penn State Harrisburg | Higher Education | Southcentral | |
| Penn State Milton S. Hershey College of Medicine | Higher Education | Southcentral | |
| Pennsylvania Bio | Support Services | Statewide | Biotechnology industry association |
| Pennsylvania College of Art & Design | Higher Education | Southcentral | |
| Penox Technologies, Inc. | Company | Northeast | Manufacturer of medical equipment |
| Pharmachem Corp | Company | Northeast | Developer and supplier of dextran products |
| Philips Ultrasound, Inc. | Company | Northcentral | Manufacturer of ultrasound equipment |
| Piezo Resonance Innovations, Inc. | Company | Northcentral | Manufacturer of Medical Devices |
| Precision Medical, Inc. | Company | Northeast | Manufacturer of respiratory products |
| Precision Medical Devices | Company | Southcentral | Contract manufacturer of FDA-registered products |
| Precision Medical Products | Company | Northcentral | Manufacturer of medical devices |
| Presque Isle Cultures | Company | Northwest | Producer of microbial cultures and biotech product testing |
| PSU Technology Transfer Center- Office of Technology Management | Higher Education | Northcentral | |
| Pugliese Pharmaceutical Services | Company | Southeast | Precursors and additives to pharmaceutical products |
| Puritan Products | Company | Northeast | Custom formulated and specialty chemicals |
| QuantumBio, Inc. | Company | Northcentral | Developer of drug discovery software |
| Ras Therapeutics, Inc. | Company | Southcentral | |
| Restek Corporation | Company | Northcentral | Manufacturer of chromatography products |
| Rockland Immunochemicals, Inc. | Company | Northeast | Manufacturer of research tools and cGMP grade proteins |
| Saladax Biomedical | Company | Northeast | Developer of personalized chemotherapy management tools |
| Salimetrics, LLC | Company | Northcentral | Tools and services related to salivary biomarkers |
| Sanofi-Pasteur, U.S. | Company | Northeast | Manufacturer of vaccines and other biologicals |
| Scientific Systems, Inc./Lab Alliance | Company | Northcentral | Supplier of laboratory equipment |
| Shippensburg University of Pennsylvania | Higher Education | Southcentral | |
| SoftGenetics, LLC | Company | Northcentral | DNA variant analysis software tools |
| Specialized Medical Devices | Company | Southcentral | Manufacturer of medical devices |
| St. Francis University | Higher Education | Southwest | |
| StarDental Products | Company | Southcentral | Dental instruments and supplies |
| Strategic Polymer Sciences, Inc. | Company | Northcentral | Design and commercialization of advanced polymer materials |
| Supelco, Inc. | Company | Northcentral | Manufacturer of chromatography columns and related tools |
| Susquehanna University | Higher Education | Northcentral | |
| Targepeutics, Inc. | Company | Southcentral | Developer of selective molecularly targeted therapeutics to fight cancer and other diseases |
| Technology Council of Central PA | Support Services | Southcentral | Technology industry association |
| The Pennsylvania State University | Higher Education | Northcentral | |
| Thermal Product Solutions | Company | Northcentral | Pharmaceutical Equipment |
| The Ultran Group | Company | Northcentral | Developer of ultrasound for industrial and bio-medical applications |
| Thiel College | Higher Education | Northwest | |
| Third Eye Diagnostics, Inc. | Company | Northeast | Technologies for non-invasively diagnosing elevated intracranial pressure. |
| Thoren Caging Systems, Inc. | Company | Northcentral | Caging for laboratory rats |
| TRS Technologies, Inc. | Company | Northcentral | Products include scintillating crystals for medical applications and piezoelectric powders, crystals, and ceramic components |
| Tyco Electronics | Company | Southcentral | Manufacturer of electronic components |
| UBC (United Biosource Corporation) | Company | Southcentral | Patient registry and data analysis services |
| Unilife Medical Solutions, Inc. | Company | Southcentral | Contract manufacturer of medical devices |
| Unique Technologies, Inc. | Company | Southcentral | Manufacturer of microsurgical blades |
| University of Scranton | Higher Education | Northeast | |
| Weis Center for Research | Higher Education | Northcentral | |
| West Pharmaceutical Services | Company | Southcentral | Developer and manufacturer of pharmaceutical technologies |
| Widener University School of Law | Higher Education | Southcentral | |
| Wilkes University | Higher Education | Northeast | |
| Wilson College | Higher Education | Southcentral | |
| Windber Medical Center | Higher Education | Southwest | |
| York College of Pennsylvania | Higher Education | Southcentral | |
| Zerosum, Inc. | Company | Southcentral | Developing a global genetic media network for life sciences |
